Speeding up enzyme engineering computationally

نویسنده

  • Nigel S. Scrutton
چکیده

Can in silico engineering speed up the delivery of biocatalysts for the burgeoning bioeconomy? In this issue, Kamerlin and coworkers introduce CADEE [Amrein et al. (2017), IUCrJ, 4, 50-64] - a framework for Computer-Aided Directed Evolution of Enzymes - that promises to lessen the burden on 'wet lab' enzymologists when optimizing biocatalysts using laboratory-based directed evolution methods.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Speeding up the Stress Analysis of Hollow Circular FGM Cylinders by Parallel Finite Element Method

In this article, a parallel computer program is implemented, based on Finite Element Method, to speed up the analysis of hollow circular cylinders, made from Functionally Graded Materials (FGMs). FGMs are inhomogeneous materials, which their composition gradually varies over volume. In parallel processing, an algorithm is first divided to independent tasks, which may use individual or shared da...

متن کامل

Speeding up Chubanov’s Basic Procedure

It is shown that a recently proposed method by Chubanov for solving linear homogeneous systems with positive variables can be improved, both theoretically and computationally.

متن کامل

Speeding up Chubanov’s method for solving a homogeneous inequality system

It is shown that a recently proposed method by Chubanov for solving linear homogeneous systems with nonnegative variables can be improved, both theoretically and computationally.

متن کامل

Speeding up Convolutional Neural Networks with Low Rank Expansions

The focus of this paper is speeding up the application of convolutional neural networks. While delivering impressive results across a range of computer vision and machine learning tasks, these networks are computationally demanding, limiting their deployability. Convolutional layers generally consume the bulk of the processing time, and so in this work we present two simple schemes for drastica...

متن کامل

Computationally Efficient Long Horizon Model Predictive Direct Current ‎Control of DFIG Wind Turbines ‎

Model predictive control (MPC) based methods are gaining more and more attention in power converters and electrical drives. Nevertheless, high computational burden of MPC is an obstacle for its application, especially when the prediction horizon increases extends. At the same time, increasing the prediction horizon leads to a superior response. In this paper, a long horizon MPC is proposed to c...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره 4  شماره 

صفحات  -

تاریخ انتشار 2017